Wolfgang Hiddemann Selected Research

Biomarkers (Surrogate Marker)

1/2022	HERVs characterize normal and leukemia stem cells and represent a source of shared epitopes for cancer immunotherapy.
11/2018	FOXP1 expression is a prognostic biomarker in follicular lymphoma treated with rituximab and chemotherapy.
2/2017	Thirty-Month Complete Response as a Surrogate End Point in First-Line Follicular Lymphoma Therapy: An Individual Patient-Level Analysis of Multiple Randomized Trials.
1/2017	Prognostic relevance of CD163 and CD8 combined with EZH2 and gain of chromosome 18 in follicular lymphoma: a study by the Lunenburg Lymphoma Biomarker Consortium.
12/2012	The composition of the microenvironment in follicular lymphoma is associated with the stage of the disease.
7/2009	Ki-67 as a prognostic marker in mantle cell lymphoma-consensus guidelines of the pathology panel of the European MCL Network.
8/2007	Tumor sclerosis but not cell proliferation or malignancy grade is a prognostic marker in advanced-stage follicular lymphoma: the German Low Grade Lymphoma Study Group.

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Wolfgang Hiddemann Research Topics

Disease

75	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 05/2024 - 07/2002
45	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 12/2023 - 01/2003
34	Neoplasms (Cancer) 01/2022 - 07/2002
28	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 04/2024 - 01/2003
24	Lymphoma (Lymphomas) 03/2024 - 01/2003
23	Leukemia 01/2022 - 09/2002
17	Non-Hodgkin Lymphoma (Lymphosarcoma) 03/2024 - 01/2003
7	Hematologic Neoplasms (Hematological Malignancy) 01/2023 - 12/2004
7	Disease Progression 05/2020 - 06/2003
7	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2018 - 06/2002
6	Acute Promyelocytic Leukemia 12/2021 - 01/2002
5	Residual Neoplasm 12/2023 - 03/2006
5	Sarcoma (Soft Tissue Sarcoma) 04/2018 - 07/2002
4	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 11/2023 - 01/2019
4	Infections 10/2018 - 09/2002
4	Hyperthermia 04/2018 - 07/2002
4	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 12/2016 - 08/2003
4	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 04/2009 - 12/2004
3	Myeloid Leukemia (Leukemia, Myelocytic) 01/2020 - 01/2003
3	Pathologic Complete Response 01/2018 - 11/2004
2	B-Cell Lymphoma (Lymphoma, B Cell) 10/2023 - 01/2015
2	Death (Near-Death Experience) 01/2017 - 11/2012
2	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 01/2016 - 05/2006
2	Graft vs Host Disease (Graft-Versus-Host Disease) 10/2012 - 01/2005
2	Trisomy (Trisomies) 07/2011 - 09/2002
2	Genetic Translocation (Chromosomal Translocation) 12/2009 - 01/2009
2	Neutropenia 04/2009 - 09/2003
2	Chromosome Aberrations (Chromosome Abnormalities) 04/2007 - 09/2002
1	Thrombocytopenia (Thrombopenia) 12/2022

Drug/Important Bio-Agent (IBA)

38	Rituximab (Mabthera)FDA Link 04/2024 - 01/2003
18	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2023 - 01/2003
15	obinutuzumabIBA 07/2023 - 02/2015
15	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2023 - 09/2003
13	Cytarabine (Cytosar-U)FDA LinkGeneric 04/2024 - 12/2003
13	GalliumIBA 12/2023 - 10/2018
12	Vincristine (Oncovin)FDA LinkGeneric 01/2023 - 09/2003
12	Monoclonal AntibodiesIBA 01/2020 - 04/2003
11	Prednisone (Sone)FDA LinkGeneric 01/2023 - 12/2004
9	AntibodiesIBA 01/2023 - 06/2003
9	Proteins (Proteins, Gene)FDA Link 08/2013 - 08/2002
8	Mitoxantrone (Novantrone)FDA LinkGeneric 12/2018 - 01/2003
7	Biomarkers (Surrogate Marker)IBA 01/2022 - 08/2007
6	Bortezomib (Velcade)FDA Link 04/2024 - 06/2003
6	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 07/2003
6	fludarabineIBA 01/2018 - 06/2002
6	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2014 - 02/2003
5	RNA (Ribonucleic Acid)IBA 05/2024 - 08/2003
5	Bendamustine Hydrochloride FDA Link 12/2020 - 07/2007
5	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2014 - 11/2002
4	Tretinoin (Retinoic Acid)FDA LinkGeneric 12/2021 - 08/2003
4	Interferon-alpha (Interferon Alfa)IBA 09/2021 - 11/2004
4	Core Binding Factors (Core-Binding Factor)IBA 01/2020 - 04/2005
4	Etoposide (VP 16)FDA LinkGeneric 04/2018 - 04/2005
3	Dexamethasone (Maxidex)FDA LinkGeneric 04/2024 - 08/2016
3	Cisplatin (Platino)FDA LinkGeneric 01/2023 - 09/2002
3	CytokinesIBA 01/2020 - 09/2003
3	Ifosfamide FDA LinkGeneric 04/2018 - 01/2006
3	Phosphotransferases (Kinase)IBA 12/2014 - 02/2006
3	Proteasome InhibitorsIBA 06/2012 - 09/2008
3	Cyclin D1IBA 12/2009 - 01/2009
3	OligonucleotidesIBA 10/2009 - 08/2003
3	CCAAT-Enhancer-Binding Protein-alphaIBA 02/2006 - 07/2002
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 03/2024 - 10/2003
2	venetoclaxIBA 12/2022 - 12/2020
2	NucleotidesIBA 10/2021 - 01/2016
2	Daunorubicin (Cerubidine)FDA LinkGeneric 01/2020 - 12/2003
2	Chlorambucil (Leukeran)FDA Link 01/2018 - 09/2006
2	Complement System Proteins (Complement)IBA 11/2016 - 01/2005
2	CreatinineIBA 08/2016 - 10/2012
2	fms-Like Tyrosine Kinase 3IBA 01/2016 - 05/2005
2	purineIBA 01/2015 - 09/2004
2	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 11/2009 - 11/2006
2	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 06/2009 - 04/2003
2	pegfilgrastim (Neulasta)FDA Link 04/2009 - 09/2003
2	ProteomeIBA 12/2007 - 11/2006
2	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 12/2006 - 07/2003
2	ibritumomab tiuxetan (Zevalin)FDA Link 08/2006 - 01/2005
2	NucleophosminIBA 06/2006 - 12/2005
2	Transcription Factors (Transcription Factor)IBA 08/2005 - 07/2003
2	promyelocytic leukemia-retinoic acid receptor alpha fusion oncoproteinIBA 04/2005 - 01/2002
2	CD40 Ligand (CD40L)IBA 09/2002 - 09/2002
1	Gemcitabine FDA Link 03/2024
1	Dihydrotachysterol (AT 10)IBA 01/2023

Therapy/Procedure

71	Therapeutics 04/2024 - 06/2002
46	Drug Therapy (Chemotherapy) 03/2024 - 01/2003
15	Stem Cell Transplantation 03/2024 - 11/2004
7	Chemoradiotherapy 01/2023 - 11/2003
5	Immunotherapy 01/2022 - 07/2007
5	Transplantation 01/2016 - 01/2004
4	Salvage Therapy 01/2020 - 09/2006
4	Induction Chemotherapy 01/2018 - 01/2009
4	Palliative Care (Palliative Therapy) 01/2017 - 04/2005
3	Homologous Transplantation 02/2014 - 07/2005
3	Time-to-Treatment 12/2012 - 03/2005
2	Cell Transplantation 01/2022 - 07/2011
2	Neoadjuvant Therapy 04/2018 - 07/2002
2	Critical Care (Surgical Intensive Care) 01/2017 - 01/2016
2	Hematopoietic Stem Cell Transplantation 01/2016 - 01/2013
2	Radioimmunotherapy 08/2006 - 07/2005
1	Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation) 01/2023